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Over the past two decades the benefits of label-free biosensor analysis have begun to make an impact in the market, and systems are beginning to be used as mainstream research tools in many drug discovery laboratories. Label-Free Technologies For Drug Discovery...
Editeur :
Wiley
Parution :
2011-02-11
PDF, ePub
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This book guides the reader through FDA regulation guidelines and outlines a comprehensive strategy for cost reduction in regulatory affairs and compliance.This book explains six strategies to cost-effectively comply with FDA regulations while maintaining product safety...
Editeur :
Wiley
Parution :
2011-02-11
PDF, ePub
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This book gives pharmaceutical scientists an up-to-date resource on protein aggregation and its consequences, and available methods to control or slow down the aggregation process. While significant progress has been made in the past decade, the current understanding of...
Editeur :
Wiley
Parution :
2010-12-28
ePub
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G protein-coupled receptors (GPCRs) are a large protein family of transmembrane receptors vital in dictating cellular responses. GPCRs are involved in many diseases, but are also the target of around half of all modern medicinal drugs. Shifting Paradigms inG Protein...
Editeur :
Wiley
Parution :
2010-12-10
PDF, ePub
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This topical reference and handbook addresses the chemistry, pharmacology, toxicology and the patentability of prodrugs, perfectly mirroring the integrated approach prevalent in today's drug design. It summarizes current experiences and strategies for the rational...
Editeur :
Wiley-VCH
Parution :
2010-11-29
Collection :
Methods & Principles in Medicinal Chemistry
PDF, ePub
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Chemokines are hormone-like signaling molecules secreted by cells to signal infection and guide the immune response. Following a decade of basic chemokine research, the pharmaceutical industry has now begun to exploit this crucial signaling pathway for the development...
Editeur :
Wiley-VCH
Parution :
2010-09-23
Collection :
Methods & Principles in Medicinal Chemistry
PDF, ePub
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Pharmaceutical and Biomedical Portfolio Management in a Changing Global Environment explores some of the critical forces at work today in the complex endeavour of pharmaceutical and medical product development. Written by experienced professionals, and including...
Editeur :
Wiley
Parution :
2010-08-03
Collection :
Wiley Series on Technologies for the Pharmaceutical Industry
PDF
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In this ground-breaking practical reference, the family of aspartic acid proteases is described from a drug developer's perspective. The first part provides a general introduction to the family of aspartic acid proteases, their physiological functions, molecular...
Editeur :
Wiley-VCH
Parution :
2010-07-28
Collection :
Methods & Principles in Medicinal Chemistry
PDF, ePub
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"Dr. Paris has written an honest, balanced presentation of the ways in which psychiatric drugs are evaluated and prescribed. He highlights the complexity of the task, the limits of what is known and the mixed picture that research often produces. His conclusions are...
Editeur :
Wiley
Parution :
2010-07-06
PDF, ePub
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The ultimate Canadian guide to prescription medication Over half of all Canadians take at least one prescription drug, but most of us know very little about the medication we're taking, including why we've been prescribed anything in the first place. Understanding...
Editeur :
For Dummies
Parution :
2010-06-28
PDF
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Born out of a project of the IUPAC's committee on Medicinal Chemistry and Drug Development, this reference addresses past and current strategies for successful drug analog development, extending the previously published volume by nine new analog classes and eight case...
Editeur :
Wiley-VCH
Parution :
2010-06-24
PDF, ePub
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ExpDesign Studio facilitates more efficient clinical trial design This book introduces pharmaceutical statisticians, scientists, researchers, and others toExpDesign Studio software for classical and adaptive designs of clinical trials. It includes the Professional...
Editeur :
Wiley-Interscience
Parution :
2010-06-15
PDF, ePub
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An integrated overview of modern approaches to lead discovery Lead generation is increasingly seen as a distinct and success-determining phase of the drug discovery process. Over recent years, there have been major advances in the understanding of what constitutes a...
Editeur :
Wiley
Parution :
2010-04-07
PDF
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Although clinical trials were virtually unheard of in psychiatry for many years, they are now the gold standard for judging whether drugs are safe and useful. But should they be? What is the true status of clinical trials? Even when they ostensibly demonstrate a benefit...
Editeur :
Wiley
Parution :
2010-03-16
PDF
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BACE inhibitors and their use in the treatment of Alzheimer's DiseaseBACE (ß-site of APP cleaving enzyme) is a critical component in Alzheimer's Disease (AD), and the development ofBACE inhibitors shows great potential as a therapy for the disease. BACE: Lead Target for...
Editeur :
Wiley
Parution :
2010-03-05
PDF
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Apply adaptive research to improve results in drug development The pharmaceutical industry today faces a deepening crisis: inefficiency in its core business, the development of new drugs. The Agile Approach to Adaptive Research offers a solution. It outlines how...
Editeur :
Wiley
Parution :
2010-02-18
Collection :
Wiley Series on Technologies for the Pharmaceutical Industry
PDF
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Examines the emerging therapeutic role of TRPV1 TRPV1 is considered an integrator of noxious stimuli and therefore may be at a crossroads for pain transmission pathways. Because of its potential for managing multiple pain types, including osteoarthritis, chronic low...
Editeur :
Wiley
Parution :
2010-02-12
PDF
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The science and applied approaches of enzyme inhibition in drug discovery and development Offering a unique approach that includes both the pharmacologic and pharmaco-kinetic aspects of enzyme inhibition, Enzyme Inhibition in Drug Discovery and Development examines the...
Editeur :
Wiley
Parution :
2010-01-26
PDF
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Designed for pharmacy students Now updated for its Second Edition, Thermodynamics of Pharmaceutical Systems provides pharmacy students with a much-needed introduction to the mathematical intricacies of thermodynamics in relation to practical laboratory applications....
Editeur :
Wiley
Parution :
2010-01-22
PDF
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Covering the latest advances in CNS drug development, this book will guide all those involved in pre-clinical to early clinical trials. The authors describe how recent innovations can accelerate the development of novel CNS compounds, improve early detection of efficacy...
Editeur :
Wiley-Blackwell
Parution :
2010-01-22
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