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A comprehensive resource on case studies of marketed kinase drugs and promising drug trials Since the discovery of protein kinase activity in 1954, the field of protein kinase drug discovery has advanced dramatically. With the ongoing clinical success of the Bcr-Abl...
Editeur :
Wiley
Parution :
2011-09-20
Collection :
Wiley Series in Drug Discovery and Development
PDF, ePub
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An expert guide to targeting protein kinases in cancer therapy Research has shown that protein kinases can instigate the formation and spread of cancer when they transmit faulty signals inside cells. Because of this fact, pharmaceutical scientists have targeted kinases...
Editeur :
Wiley
Parution :
2011-09-20
PDF, ePub
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This book contains contributions from interdisciplinary scientists to collectively address the issue of targeting carbohydrate recognition for the development of novel therapeutic and diagnostic agents. The book covers (1) biological problems involving carbohydrate...
Editeur :
Wiley
Parution :
2011-09-09
Collection :
Wiley Series in Drug Discovery and Development
PDF, ePub
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Pharmacovigilance is the science and activities relating to the detection, assessment, understanding and prevention of adverse effects or any other drug-related problems. This introductory guide is designed to aid the rapid understanding of the key principles of...
Editeur :
Wiley-Blackwell
Parution :
2011-08-24
ePub
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Complete, up-to-date coverage of the broad area of nucleic acid chemistry and biology Assembling contributions from a collection of authors with expertise in all areas of nucleic acids, medicinal chemistry, and therapeutic applications, Medicinal Chemistry of Nucleic...
Editeur :
Wiley
Parution :
2011-08-10
Collection :
Wiley Series in Drug Discovery and Development
PDF, ePub
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The book addresses the basics, applications, and manufacturing of plasmid biopharmaceuticals.The survey of the most relevant characteristics of plasmids provides the basics for designing plasmid products (applications) and processes (manufacturing). Key features that...
Editeur :
Wiley
Parution :
2011-08-04
PDF, ePub
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This book overviews and integrates the business and technical issues that pharmaceutical companies need to know in order to combat the major global problem of counterfeit medicines. In addition to discussion of the problems, the author Davison addresses analytical...
Editeur :
Wiley
Parution :
2011-08-04
PDF, ePub
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Drug discrimination: a practical guide to its contributions to the invention of new chemical entities and evaluations of new or known pharmacological agentsDrug discrimination can be described as a "drug detection" procedure that uses a pharmacologically active agent as...
Editeur :
Wiley
Parution :
2011-08-04
PDF, ePub
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Understand and assess the design, delivery, and efficacy of orally administered drugs A practical guide to understanding oral bioavailability, one of the major hurdles in drug development and delivery, Oral Bioavailability: Basic Principles, Advanced Concepts, and...
Editeur :
Wiley
Parution :
2011-08-04
Collection :
Wiley Series in Drug Discovery and Development
PDF, ePub
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Discover new and emerging applications for microdialysis in drug evaluation Microdialysis is a highly valuable sampling tool that can be used in vivo to measure free, unbound analyte concentrations located in interstitial and extracellular spaces. This book explores the...
Editeur :
Wiley
Parution :
2011-07-13
PDF, ePub
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The new edition of Principles and Practice of Pharmaceutical Medicine is a comprehensive reference guide to all aspects of pharmaceutical medicine. New content includes chapters and coverage on regulatory updates, increasing international harmonization, transitional and...
Editeur :
Wiley-Blackwell
Parution :
2011-07-12
PDF, ePub
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This book focuses on new small molecule approaches to combat viral infections. The chapters describe the discovery and development from bench through the clinic of relatively recently-approved antiviral drugs and compounds in advanced clinical development. Organized by...
Editeur :
Wiley
Parution :
2011-07-08
ePub
Offre spéciale
-9%
65,36€
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Are you about to sit your pharmacology exams? Do you lack confidence in prescribing? Would it help to have a quick reference, pocket-sized reassurance on common drugs and the conditions that they are used in? The Hands-on Guide to Clinical Pharmacology is the perfect...
Editeur :
Wiley-Blackwell
Parution :
2011-06-20
Collection :
Hands-on Guides
PDF, ePub
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The definitive book on the neutralization of recombinant biopharmaceuticals Recombinant biopharmaceuticals are an important tool for treating a range of illnesses; however, their efficacy can be severely impaired by their immunogenicity. When introduced into the body,...
Editeur :
Wiley
Parution :
2011-06-09
PDF, ePub
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By focusing on general molecular mechanisms of antiviral drugs rather than therapies for individual viruses, this ready reference provides the critical knowledge needed to develop entirely novel therapeutics and to target new viruses. It begins with a general discussion...
Editeur :
Wiley-VCH
Parution :
2011-04-08
Collection :
Methods & Principles in Medicinal Chemistry
PDF, ePub
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Drug discovery is all about finding small molecules that interact in a desired way with larger molecules, namely proteins and other macromolecules in the human body. If the three-dimensional structures of both the small and large molecule are known, their interaction...
Editeur :
Wiley-VCH
Parution :
2011-03-31
Collection :
Methods & Principles in Medicinal Chemistry
PDF, ePub
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This book examines genotoxic impurities and their impact on the pharmaceutical industry. Specific sections examine this from both a toxicological and analytical perspective. Within these sections, the book defines appropriate strategies to both assess and ultimately...
Editeur :
Wiley
Parution :
2011-03-29
ePub
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A must-have guide for any professional in the drug manufacturing industry The Good Clinical Practice (GCP) audit is a tedious but necessary exercise that assures that all parties do their job properly and in compliance with the applicable FDA code. Clinical Trials...
Editeur :
Wiley
Parution :
2011-03-01
PDF
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RNA Interference: Application to Drug Discovery and Challenges to Pharmaceutical Development provides a general overview of this rapidly emerging field, with a strong emphasis on issues and aspects that are important to a drug development team. The first part covers...
Editeur :
Wiley
Parution :
2011-03-01
ePub
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The focus of early drug development has been the submission of an Investigational New Drug application to regulatory agencies. Early Drug Development: Strategies and Routes to First-in-Human Trials guides drug development organizations in preparing and submitting an...
Editeur :
Wiley
Parution :
2011-02-25
PDF, ePub
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