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G protein-coupled receptors (GPCRs) are membrane proteins that transduce a vast array of extracellular signals into intracellular reactions ranging from cell-cell communication processes to physiological responses. They play an important role in a variety of diseases...
Editeur :
Wiley
Parution :
2008-03-11
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Drug-Drug Interactions in Pharmaceutical Development comprehensively reviews the relevant science, industrial practice, and regulatory agency positions on drug-drug interactions. It focuses on the evaluation of potential drug-drug interactions, allowing researchers to...
Editeur :
Wiley-Interscience
Parution :
2008-03-05
Collection :
Wiley Series in Drug Discovery and Development
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The authoritative reference on High Content Screening (HCS) in biological and pharmaceutical research, this guide covers: the basics of HCS: examples of HCS used in biological applications and early drug discovery, emphasizing oncology and neuroscience; the use of HCS...
Editeur :
Wiley-Interscience
Parution :
2008-01-18
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Iminosugars form undoubtedly the most attractive of carbohydrate mimics reported so far. In these structures, the substitution of the endocyclic oxygen of sugars by a basic nitrogen atom leads to remarkable biological properties and raises many challenges in organic...
Editeur :
Wiley
Parution :
2007-10-22
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The long awaited second edition of Principles and Practice of Pharmaceutical Medicine provides an invaluable guide to all areas of drug development and medical aspects of marketing.The title has been extensively revised and expanded to include the latest regulatory and...
Editeur :
Wiley
Parution :
2007-04-30
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As a result of the expansion in the area of pharmaceutical medicine there is an ever-increasing need for educational resources. The Dictionary of Clinical Trials, Second Edition comprehensively explains the 3000 words and short phrases commonly used when designing,...
Editeur :
Wiley
Parution :
2007-04-30
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"... this text takes a novel approach... The style... is not as dry as other statistics texts, and so should not be intimidating even to a relative newcomer to the subject... The layout is easy to navigate, there are chapter aims, summaries and “key point boxes”...
Editeur :
Wiley
Parution :
2007-04-04
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Pharmacometrics is the science of interpreting and describing pharmacology in a quantitative fashion. The pharmaceutical industry is integrating pharmacometrics into its drug development program, but there is a lack of and need for experienced pharmacometricians since...
Editeur :
Wiley-Interscience
Parution :
2007-03-16
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Medical devices are crucial in medical care today and device technology advances at a dizzying pace.Medical Device Epidemiology and Surveillance is the first book to provide an overview of medical device epidemiology and surveillance as well as perspectives from...
Editeur :
Wiley
Parution :
2007-03-13
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This timely and original handbook paves the way to success in plant-based drug development, systematically addressing the issues facing a pharmaceutical scientist who wants to turn a plant compound into a safe and effective drug. Plant pharmacologists from around the...
Editeur :
Wiley-VCH
Parution :
2006-12-13
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This book is the first to address the most urgent issues, combining a solid basic research approach with applied individual and stress issues, including interventions. Throughout, the focus is on our latest knowledge about various causes of stress and its...
Editeur :
Wiley-Blackwell
Parution :
2006-12-13
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In this new edition of a bestseller, all the contents have been updated and new material has been added, especially in the areas of toxicity testing and high throughput analysis. The authors, all of them employed at Pfizer in the discovery and development of new active...
Editeur :
Wiley-VCH
Parution :
2006-08-21
Collection :
Methods & Principles in Medicinal Chemistry
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Principles of Psychopharmacology for Mental Health Professionals addresses the current "split" model of mental health care, in which physicians provide pharmaco-therapy while non-prescribing practitioners oversee other services such as psychotherapy. Bringing these two...
Editeur :
Wiley-Liss
Parution :
2006-07-21
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A unique, holistic approach covering all functions and phases of pharmaceutical research and development While there are a number of texts dedicated to individual aspects of pharmaceutical research and development, this unique contributed work takes a holistic and...
Editeur :
Wiley-Interscience
Parution :
2006-07-11
Collection :
Wiley Series in Drug Discovery and Development
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Statistics show that out of five thousand compounds with initial promise, five will go into human clinical trials, and only one will become an approved drug. This tiny fraction illustrates the huge complexities involved in bringing a drug to market, a process that...
Editeur :
Wiley-Liss
Parution :
2005-03-11
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A key text for all those involved in pharmacovigilance. Detection of new adverse drug reactions is fundamental to the protection of patients from harm that may occur as a result of medication. This book explores the methods used to investigate new adverse drug...
Editeur :
Wiley
Parution :
2004-11-19
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Treatment with drugs is fundamental to modern therapy of psychiatric disorders. The number of disorders responsive to drug treatment is increasing, reflecting the extensive synthesis of novel compounds and the greater understanding of the aetiology of the disorders. ...
Editeur :
Wiley
Parution :
2004-05-03
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Studies of thermodynamics often fail to demonstrate how the mathematical intricacies of the subject relate to practical laboratory applications. Thermodynamics of Pharmaceutical Systems makes these connections clear, emphasizing specific applications to pharmaceutical...
Editeur :
Wiley-Liss
Parution :
2003-04-02
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